WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Lysosome       ID:04142
C=121; O=5; E=0.20; R=25.46; rawP=1.67e-06; adjP=1.67e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
2  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
3  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
4  ENSG00000117984 NA CTSD cathepsin D 1509 ENSG00000117984
5  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:KEGG pathway       Name:Gastric acid secretion       ID:04971
C=74; O=3; E=0.12; R=24.98; rawP=0.0002; adjP=0.0010
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092820 NA EZR ezrin 7430 ENSG00000092820
2  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
3  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918


Database:KEGG pathway       Name:Glycosaminoglycan biosynthesis - chondroitin sulfate       ID:00532
C=22; O=2; E=0.04; R=56.01; rawP=0.0006; adjP=0.0020
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
2  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989


Database:KEGG pathway       Name:Vibrio cholerae infection       ID:05110
C=54; O=2; E=0.09; R=22.82; rawP=0.0035; adjP=0.0076
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
2  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:KEGG pathway       Name:Pathogenic Escherichia coli infection       ID:05130
C=56; O=2; E=0.09; R=22.00; rawP=0.0038; adjP=0.0076
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092820 NA EZR ezrin 7430 ENSG00000092820
2  ENSG00000176014 NA TUBB6 tubulin, beta 6 class V 84617 ENSG00000176014


Database:KEGG pathway       Name:Protein digestion and absorption       ID:04974
C=81; O=2; E=0.13; R=15.21; rawP=0.0077; adjP=0.0128
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
2  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918


Database:KEGG pathway       Name:Pancreatic secretion       ID:04972
C=101; O=2; E=0.16; R=12.20; rawP=0.0118; adjP=0.0169
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
2  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918


Database:KEGG pathway       Name:Phagosome       ID:04145
C=153; O=2; E=0.25; R=8.05; rawP=0.0258; adjP=0.0323
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000176014 NA TUBB6 tubulin, beta 6 class V 84617 ENSG00000176014
2  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:KEGG pathway       Name:Protein processing in endoplasmic reticulum       ID:04141
C=165; O=2; E=0.27; R=7.47; rawP=0.0296; adjP=0.0329
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000089248 NA ERP29 endoplasmic reticulum protein 29 10961 ENSG00000089248
2  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506


Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=5; E=1.83; R=2.73; rawP=0.0366; adjP=0.0366
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
3  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989
4  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553
5  ENSG00000134333 NA LDHA lactate dehydrogenase A 3939 ENSG00000134333




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).